http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5492951-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eea080e03bbd9386a81a90c22aa8bf43 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H15-234 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-234 |
| filingDate | 1977-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44c568e024775840702c690ec6ecafbd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a20a72d88ffce5b71ceea73ded20638f |
| publicationDate | 1979-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S5492951-A |
| titleOfInvention | Novel aminoglycoside derivative |
| abstract | NEW MATERIAL:Compounds of formula I (R is H, alkyl, aralkyl; R 1 is aminomethyl, hydroxymethyl; R 2 , R 3 and R 6 are H or OH; R 4 is OH or NH 2 ; R 5 is NH 2 or methylamino; R 7 is OH or methyl; R 8 is H or hydroxymethyl; n is 1, 2 or 3; broken line exhibits the presence or absence of double bond). n EXAMPLE: 1-N-[3-Hydroxyazetidine-3-yl)methyl]tobramycin sulfate salt. n USE: Medicines for man and animal, food additive as antibacterial agent, disinfectants, these compound has strong antibacterial activity against grampositive and -negative bacteria. n PREPARATION: The reduction of a compound of formula II is carried out using 1W2 equivalent amount of lithiumaluminum hydride per mole of the compound in an anhydrous solvent under an atmosphere of inert gas for 1W8 hr to produce the objective compound of formula I. n COPYRIGHT: (C)1979,JPO&Japio |
| priorityDate | 1977-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 19.