http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5492949-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_630b360599ea5cf4b5bcbc0c6c0a3e2d |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J7-00 |
| filingDate | 1977-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c5e624ce4752b821c2e62b9a2eb0b93a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c0400091c83cfca6ce2662d85398c5c9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_38670ef1339793e0feb67c054fca5682 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c35086d659bed182865b1f5c9c2c4af4 |
| publicationDate | 1979-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S5492949-A |
| titleOfInvention | Production of 3,17-dihydroxypregn-5-ene-29-ine |
| abstract | PURPOSE: Androst-4-ene-3,17-dione is reacted with a metal acetylide and the product is reduced with alkali metal borohydride to produce readily title compound used as intermediate for synthesizing spinolactone, a diuretic agent, in high yield. n CONSTITUTION: The reaction of androst-4-ene-3,17-dione (abbreviated to 4AD hereinafter) with a metal acetylide as potassium acetylide is carried out in a hydrophilic organic solvent as tetrahydrofuran to ethynylate the carbonyl group selectively in the 17 position. Then the pH of the reaction mixture is made to 9W13 and the reduction is effected using alkali metal borohydride to produce 3,.17-dihydroxypregn-5-ene-20-ine. n COPYRIGHT: (C)1979,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S54145647-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5495553-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6135999-B2 |
| priorityDate | 1977-12-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.