http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5492930-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1374dd16777534b65ad4422333245af8 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C313-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 |
filingDate | 1977-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd10080b788f1e6d38ebda3ca8544e0e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d72057e3c2c01eecbd2ab0fa5391442 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a3e031c2c78c88ee6aed81c1b9b7b78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc73a53703b5cdb6582ae13ea7614f2c |
publicationDate | 1979-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S5492930-A |
titleOfInvention | Para-substituted phenethylalcohol derivative and its preparation |
abstract | NEW MATERIAL:Para-substituted phenethyl alcohol derivatives of formula I (R 1 is lower alkyl; R 2 is H or R 1 ). n EXAMPLE: 2-(p-Methylthiomethylphenyl)-1-propanol. n USE: Medicines as analgesics antiflammatory agents, antithrombotic agents and antiartoriosclerotic agents. n PREPARATION: The reduction of a para-substituted phenylacetic derivative of formula II (R 3 =R 2 ) as methyl 2-(p-methylthiomethylphenyl) propionate is conducted using a large excess amount of a reducing agent as lithium aluminum hydride in a solvent as ether, then the excess reducing agent is decomposed with a saturated sodium sulfate solution in water to obtain the high-purity objective compound of formula I. Especially the compound of formula III (R 11 is lower alkyl of 1W5 carbon atoms; R 21 is H or methyl) is preferred. n COPYRIGHT: (C)1979,JPO&Japio |
priorityDate | 1977-12-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.