| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8f4c2477bdea308bc9dec3feded37457 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-553 |
| filingDate |
1977-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51ab5b691a918a35bf0984ef63ddadea
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_772dbc9f968f9d749156cbefbba77cce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_665f0c38a7a12b0aaaa24d8ee18b3fcd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f78bf9c679e8620f4a8295b00284dfdd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_890618275fa1bb30e12c26173b8991da |
| publicationDate |
1979-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-S5455582-A |
| titleOfInvention |
5-fluorouracil and antitumorigenic agent containing the same as major effective component. |
| abstract |
NEW MATERIAL:5-Fluorouracils of formula I (R is l-6C alkyl). n EXAMPLE: N 1 -ethoxycarbonyl-5-fluorouracil. n USE: Antitumorigenic agent: it has extremely much lower toxicity than 5-FU and FT-207 and larger factor of safety. n PREPARATION: Equimolar amounts of 5-fluorouracil and a lower alkoxycarbonyl chloride of formula III (X is halogen) are reacted at room temperature -50°C to form a compound of formula I. The 5-fluorouracil is converted to its metal salt when used for the reaction and the solvent used is preferably dimethylformamide, or dimethylacetamide n COPYRIGHT: (C)1979,JPO&Japio |
| priorityDate |
1977-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |