http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5452068-A

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-08
filingDate 1977-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e74cfe293e43f1fc1a6870b8b622f88
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publicationDate 1979-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S5452068-A
titleOfInvention 2-azetidinone derivative and its preparation
abstract NEW MATERIAL:2-Azetidinone derivatives I (R 1 is H, OH, alkoxy, substituted or unsubstituted aralkyloxy, etc.; R 2 is alkyl, aralkyl; R 3 is alkyl aryl, aralkyl, etc.; R 4 is alkyl, alkenyl, aryl, etc.; R 2-4 may have substitution groups), pref. an optically active 2-azetidinone derivative II. n EXAMPLE: (4S)-t-butyl-α-(4-benzyloxycarbonyl-2-oxoazetidin-1-yl)-α-(acetyl) acetamide. n USE: The compound has β-lactamase-inhibiting activity, and useful for the remedy of infectious diseases together with other antibiotics such as penicillin. It is also useful as an intrmediate f a compound having a skelton similar to the β-lactam antibiotics. n PROCESS: The compound I is prepared by the condensation reaction of the compound III with the compound IV and the compound V in a proper solvent n COPYRIGHT: (C)1979,JPO&Japio
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5610165-A
priorityDate 1977-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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