http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S5441314-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_204ea9f0f83d1c51a916e46a41a6a14a |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-618 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-56 |
| filingDate | 1977-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c298ae35bc33411848955ee89df8d1c3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fef8c9cb766bafd47f19c127ed69696 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_19b221166057fb16e3e7b74e735b6f6c |
| publicationDate | 1979-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S5441314-A |
| titleOfInvention | Anti-tumor substance and its preparation |
| abstract | PURPOSE: To prepare a water-soluble, non-cytotoxic, saccharide-containing proteinic anti-tumor substance A having broad anti-cancer spectrum, and strong anti-tumor activity, by removing liver from shellfish, esp. scallop, extraction the flesh or adductor of the shellfish, with water and separating and purifying the objective compound from the extract. n CONSTITUTION: Liver is removed from shell fish, and the flesh or adductor thus obtained is homogenized in water, a salt solution, or a buffer solution. The homogenized mixture is filtrated, or centrifuged to obtain extract. Anti-tumor substances A 1 , A 2 , A 3 , and A 4 are separated from the extract purified by a proper combination of salting-out, treatment with organic solvents, ultra-filtration, gel-filtration, chromatography, electrophoresis, etc. These substances are water-soluble, saccharide- containing proteins whose characteristics are as follows: white or slightly yellowish white solid, insoluble in organic solvents: amphoteric electrolyte: main absorption peaks of IR spectrum, 1658cm -1 , 1550cm -1 , average molecular weight, about 20,000. n COPYRIGHT: (C)1979,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S57130918-A |
| priorityDate | 1977-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID962 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419512635 |
Total number of triples: 19.