abstract |
PURPOSE: Prostaglandin I 2 analogue compounds of formula I: (Y is ethylene or trans-vinylene group: R 1 is H or 1-12C alkyl group: R 2 is H, methyl, or ethyl group; R 3 is single bond, 1-4C alkylene group; R 4 is H, 1-8C alkyl group, etc. and one of R 5 , R 6 , and R 7 is 1-4C alkyl group, and the other two are H, the wavy lines attached to the carbon atoms at the 2-,3-,4-,11-, and 15-positions are α- or β-configuration, and the double bond between the 5- and 6-positions is Z). n COPYRIGHT: (C)1979,JPO&Japio |