http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S54157539-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e7962109cd4763907b82b66760cd0ae8 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-36 |
| filingDate | 1978-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c0ccdcded6cc7480a0877f03cf3a1fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4e37d82fa30205d3b3d51f872402588 |
| publicationDate | 1979-12-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S54157539-A |
| titleOfInvention | Preparation of 4-oxo-4-phenyl-2-substituted-amino-2-butenoic acid alkyl esters |
| abstract | PURPOSE: To prepare the title compound which is an intermediate of 3-phenyl- substituted pyrroles useful as antibacterial agents, in high yield, by reacting a benzoyl-pyruvic acid alkyl ester with an α-amino acid alkyl ester salt in an organic solvent in the presence of a weak base. n CONSTITUTION: The objective compound III (e.g. the compound IV) is prepared by reacting a benzolypyruvic acid alkyl ester I (X is halogen, nitro, alkyl, halogenated alkyl, alkoxy; n is 1W3; R is alkyl) [e.g. 3-(3-chlorobenzoyl)pyruvic acid ethyl ester] with a salt of an α-amino acid alkyl ester II (R' is alkyl; R'' is H, alkoxycarbonyl, etc.) (e.g. aminomalonic acid diethyl ester hydrochloride in an organic solvent (e.g. benzene) in the presence of a weak base (e.g. pyridine). n EFFECT: The objective compound can be obtained in high selectivity. n COPYRIGHT: (C)1979,JPO&Japio |
| priorityDate | 1978-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.