http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S54154754-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_204ea9f0f83d1c51a916e46a41a6a14a |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D305-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-335 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-365 |
| filingDate | 1978-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9fef8c9cb766bafd47f19c127ed69696 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92b5dbdbb2968008aeb158620c8ee760 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_539818fce596ac21edbf6dd773d74c68 |
| publicationDate | 1979-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S54154754-A |
| titleOfInvention | Beta-lactone derivative of antiesterase active substance delta-hydroxymicolic acid and its preparation |
| abstract | NEW MATERIAL:A 3,5-dihydroxy-2-hexylhexadeca-7,10-dienoic 1,3-lactone of formula I and 3,5-dihydroxy-2-hexylhexadecanoic 1,3-lactone of formula II. n USE: Antiesterase active substances having enlarged inhibitory enzyme groups compared with esterastin, a particularly powerful anticholesterol activity, and expected possibility of application as a remedy for thromosis and arteriosclerosis in addition to arthritis and rheumatic fever. n PROCESS: Esterastin of formula III: [R is CH 3 -(CH 2 ) 4 -CH=CH-CH 2 -CH=CH-CH 2 or CH 3 -(CH 2 ) 10 ] or tetrahydroesterastin is hydrolyzed with an alkali to give the objective compound of formulas I and II. The compound of formula I thus obtained is catalytically reduced to give the objective compound of formula II. n COPYRIGHT: (C)1979,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S61152664-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0564953-B2 |
| priorityDate | 1978-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.