| abstract |
PURPOSE: ProstaglandinI 2 analogs of formula I[Y is trans vinylene, ethylene; R 1 is H, 1 - 12C alkyl; R 2 is H, methyl or so; R 3 is single bond or 1 - 4C alkylene; R 4 is H, 1 - 8C alkylene or so; R 5 is 1 - 4C alkyl; W is α- and/or β-conformation; the double bond between C 5 and C 6 shows Z]., and their clathrate compounds with cyclodextrin, and their nontoxice acid salts when R 1 is H. n COPYRIGHT: (C)1979,JPO&Japio |