http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S54144400-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_01c1e0bc0628f76dea731cda5a666ca1 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-08 |
filingDate | 1978-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41d3a10e23c077ef2dc703175bbf1ba4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a7d3979e29bc356efe90e03ff06edd7 |
publicationDate | 1979-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S54144400-A |
titleOfInvention | Preparation of rifamycin derivative |
abstract | PURPOSE: To prepare 3-iminomethyl derivative of rifamycin SV, easily, in high yield, by the two stage reaction from rifamycin B or O via 3-iminomethyl derivative of rifamycin S. n CONSTITUTION: Rifamycin B or rifamycin O is converted to 3-iminomethyl derivative of rifamycin S of formula I (R is alkyl) by reacting with HCHO and a primary amine or with an aldiimino derivative of HCHO and a primary amine, in the presence of an oxidizing agent. The reaction product (1 mole) is further made to react with (substituted-)hydrazine (≥2 moles) to afford the objective 3-iminomethyl derivative of rifamycin SV of formula II (R' is hydrozono, substituted hydrazono). n COPYRIGHT: (C)1979,JPO&Japio |
priorityDate | 1978-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.