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filingDate 1978-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86ef805926a2f7f7e9e8e69641c835af
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publicationDate 1979-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S54117401-A
titleOfInvention Antifungal agent neoenactin and preparation thereof
abstract NEW MATERIAL:Neoenactin, its functional derivatives and their salts. Properties thereof are as follows. Elemental analysis: C 63.47%, H 10.04%, N 7.44% (0 19.05%); specific rotation: [α] 12 D= -14.2° (c=3%, in methanol); positive to color reactions of ninhydrin, naphthoresorcinol-phosphoric acid and KMnO 4 , negative to color reactions of anthrone-phosphoric acid and α-naphthol-phosphoric acid; white amorphous powder; m.p. 60.5W64.5°C; etc. n USE: Antifungal antibiotics of non-polyene type. Increase the antifungal effect of trichomycin and amphotericin B, which are known polyene type antibiotics irrespective of the presence or absence of cholesterol. n PROCESS: Neoenactin-forming fungi (FERM-P No.4376) is caltured, and neoenactin or its constituent component is separated from the cultured medium and the cells of the fungi. n COPYRIGHT: (C)1979,JPO&Japio
priorityDate 1978-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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