http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S54106472-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_129e393582e6bdf4029baf2206522f45 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-28 |
| filingDate | 1978-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ca7812df3e9833a2e81b1908e90902b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb87359e86f19cc90d7e53100b443ac1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2472a02a90997fc8a4bcd1bc108d54d |
| publicationDate | 1979-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S54106472-A |
| titleOfInvention | Preparation of 4, 5, 6, 7-tetrahydro-benzimidazoline-2-thione |
| abstract | PURPOSE: To obtain the title compound which is an intermediate for medicines in simple procedures in high yield, by treating a specific compound, readily prepared through addition reaction between 2-amino-cyclohexanone oxime and a thioisocyanate, with an acidic substance. n CONSTITUTION: A N-(2-hydroxyimino-cyclohexyl)-thiourea of formula I: (R is alkyl, allyl, or aralkyl group) is brought into contact with an acidic substance, e.g. hydrogen chloride, hydrogen bromide, sulfuric or benzenesulfonic acid, at 0W 150°C, preferably 10W100°C to give the objective compound of formula II. The thiourea of formula I is obtained by addition reaction of 2-amino-cyclohexanone oxime with a thiocyanate of formula IV according to the well-known method. Preferably, the amount of the acidic substance is 0.01 mole or more per mole of the compound of formula I. n COPYRIGHT: (C)1979,JPO&Japio |
| priorityDate | 1978-02-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 42.