abstract |
PURPOSE: Prostaglandin analogue of formula I (Z is radical of formula II, etc.; Y is ethylene or trans-vinylene; R is 1-4C alkyl; R 1 is H, chloro, trifluoromethyl or 1-4C alkyl; double bonds of C 2 -C 3 , C 4 -C 5 and C 13 -C 14 are trans), e.g. ethyl ester of 16-phenoxy-17,18,19,20-tetranol-trans-Δ 2 , trans-Δ 4 PGE 1 α. n COPYRIGHT: (C)1978,JPO&Japio |