| abstract |
PURPOSE: Prostaglandin I 2 analogous cpds. I (Y is trans-vinylene or ethylent; R 1 is H, CH 3 or C 2 H 5 ; R 2 is direct bond or 1 - 4C alkylene; R 3 is H, alkyl, phenyl, etc.; the dotted line is α-coordination, β-coordination or their mixture; Z is the double bond between 5- and 6-positions) or their cyclodextrin inclusion cpds., e.g. (5Z, 13E) - (9α, 11α, 15S) -6, 9-epoxyprosta-5,13-diene-11, 11, 15-triol. n COPYRIGHT: (C)1978,JPO&Japio |