| abstract |
PURPOSE: Prostaglandin-like compounds of formula I (Y is trans-vinylene, ethylene; R 1 is H, C 1-12 alkyl; R 2 is H, methyl, ethyl; R 3 is a single bond, C 1-4 alkyl; R 4 is H, C 1-8 alkyl, phenyl unsubstd. or substituted with C 4-8 cycloalkyl,etc.; R 5 together with R 6 form an OXO group, or one is OH the other is H; the wavy lines attached to 11-, snd 15- carbon show α- or β-configuration or their mixture; the double bond between 13- and 14-position is trans; excluding 6-oxo-PGF 1 α, etc.). e.g. dl 6 oxo PGF 1 α. n COPYRIGHT: (C)1978,JPO&Japio |