| abstract |
PURPOSE: Prostaglandin X analogous cpds. I(Y is transvinylene or ethylene; R 1 is H or 1-12C alkyl;R 2 is H, methyl or ethyl;R 3 is a direct bond or 1-4C alkyl;R 4 is H, 1-8C alkyl, etc.;the dotted line is α-or β-coordination or their mixture;the double bond between 5-and 6-positions shows E-type cpd.) and nontoxic salts (R 1 =H), e.g. (5E, 13E)-(9α, 11α, 15S)-6, 9-epoxy-11,15-dihydroxyprosta-5, 13-dienenoic acid methylester. n COPYRIGHT: (C)1978,JPO&Japio |