| abstract |
PURPOSE: NG-Substituted-N 2 -coumarinsulfonylargininamides of the formula I [one of X and Y is a protective group of a guanidino group, and the other is H or a protective group of the guanidino group; R is-NR 1 R 2 (R 1 and R 2 are H, alkyl, aralkyl, etc.) or a cyclic amino group (e.g. 1-polymethyleneiminyl, 3oxazolidinyl, morpholino, etc.); and R' is H or alkyl], and their acid salts. For example, 4-ethyl-1-(NG-nitro-N 2 -(6-coumarinsulfonyl)-L-arginyl) piperidine may be cited. n COPYRIGHT: (C)1977,JPO&Japio |