| abstract |
PURPOSE: NG-Substituted-N 2 -(5,6,7,8-tetrahydro-1,2-naphthylenesulfonyl) argininamides of the formula I [X and Y are protective groups of a guanidino group (one of them may be H); R is a group of the formula II (R 1 and R 2 are H, C 1-10 alkyl, etc.) or the formula III(Z is a bivalent group in which 20 or less of groups of methylene, mono-substituted methylene, oxy, thio, etc. are bonding); R' is 5,6,7,8-tetrahydro-1-naphthyl, etc.], or their acid salts. For example, NGnitro-N 2 -(5,6,7,8-tetrahydro-1-naphthalenesulfonyl)-N-benzyl-N-methyl-L-argininamide may be cited. n COPYRIGHT: (C)1977,JPO&Japio |