abstract |
PURPOSE: Hydrogenated 1-oxo-isoindoline derivatives I[where ring A is cyclohexane ring having or not having two or below of non-conjugated unsaturated bond; R is H or 1 W 3C lower alkyl; B is OH, OR'''(R''' is 1 W 3C lower alkyl) or -NR'R''(R' and R'' are H or 1 W 3C lower alkyl; R' and R'' together with nitrogen atom may form a hetrocyclic ring)], e.g. α-[4'-(1-oxo-4, 7-dihydro2-isoindinyl) -phenyl] -propionic acid. n COPYRIGHT: (C)1977,JPO&Japio |