| abstract |
1416412 Piperazine and homopiperazine derivatives HOKURIKU PHARMACEUTICAL CO Ltd 7 Jan 1974 [8 Oct 1973 (3)] 00588/74 Heading C2C Novel compounds I (in which R is phenyl substituted with one or more of C 1-6 alkyl, C 1-6 alkoxy and halogen; or styryl or pyridyl optionally substituted with one or more C 1-6 alkoxy groups and n and m are 2 or 3) and salts thereof, are prepared by esterification of an alcohol of Formula (II) or a salt thereof, with an appropriate acid. Pharmaceutical compositions having analgesic, coronary vasodilative, anti-convulsant and blood pressure decreasing properties comprise one of the above novel compounds together with a pharmaceutically acceptable vehicle or diluent. |