| abstract |
(57) [Summary] [Problem] To provide a sustained-release microcapsule having a high drug content, suppressed initial release, and exhibiting stable release. A sustained-release microcapsule is produced by adding a physiologically active substance to an organic solvent solution of a biodegradable polymer containing a fat-soluble substance, particularly vitamin E, and dispersing and emulsifying the same. And sustained release microcapsules obtained by the production method. |