| abstract |
PROBLEM TO BE SOLVED: To provide a novel triazolo-1,4-diazepine compound having both PAF antagonistic action and thromboxane synthesis inhibitory action. SOLUTION: Formula (I) [Wherein, A represents CO, CO-B or B, and B represents C 1- Represents an alkylene group or an intermediate in the alkylene group C 2 -C 6 the oxygen atoms are interposed in C 6, X represents N-O or CH, n represents an integer of 2 to 6, R is a hydroxyl group C 1 a lower alkyl group or a lower alkylamino group (these groups C 1 -C 6 of -C 6 is N, N-dimethylamino group, N, N-diethylamino group, substituted with a phenyl group or heterocyclic group R 1 represents a hydrogen atom or a C 1 -C 3 lower alkyl group. And a pharmaceutically or pharmaceutically acceptable salt thereof as an active ingredient, especially an antiallergic or anti-inflammatory agent comprising the triazolo-1,4-diazepine compound represented by the formula: |