abstract |
(57) Abstract: A peptide consisting of 5 to 10 amino acid residues, having an amino acid sequence containing at least one Phe and at least one Arg or Lys, and having a specific charge. A low-density lipoprotein-selective adsorbing peptide having a specific gravity of 0; [Effect] Since it binds to LDL's apoB protein, it has excellent LDL selective adsorptivity, yet does not induce the production of bradykinin and can be circulated extracorporeally under low heparin administration conditions, such as whole blood or plasma. Can be advantageously used as a reagent for an adsorbent for removing low-density lipoprotein from body fluids. |