| abstract |
(57) [Problem] To provide a novel TNF production inhibitor. Kind Code: A1 Abstract: Formula (I) (Wherein, R 1 represents a hydrogen atom or a lower alkanoyl group, and R 2 represents a lower alkanoyl group) or a pharmaceutically acceptable acid addition salt thereof as an active ingredient. Inhibitors. The morphine derivative (I) or a pharmacologically acceptable acid addition salt thereof is useful as a therapeutic agent for diseases accompanied by abnormal production of TNF. |