| abstract |
(57) Abstract: A reversible cysteine protease inhibitor having two N-substituents linked via ethylenediamine or a substituted ethylenediamine, wherein the inhibitor has a dissociation constant K I of greater than about 100 μM in the inhibition of protease. And the N-substituent is from the group consisting of acyl, acyl peptidyl, alkyloxycarbonyl, alkyloxycarbonyl peptidyl, sulfonyl, sulfonyl peptidyl, peptidyl, sulfamoyl, sulfamoyl peptidyl, sulfinyl, sulfinyl peptidyl, carbamoyl and carbamoyl peptidyl. Selected. |