http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H11505027-A
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-975 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-587 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-94 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
filingDate | 1997-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 1999-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H11505027-A |
titleOfInvention | Uniform sol-sol assay |
abstract | (57) SUMMARY The present invention provides a method for detecting the presence of, or measuring the amount of, a ligand in a fluid sample. The method comprises the steps of providing a first reagent comprising sol particles having detectable physical properties bound to the ligand or ligand analog (in a competitive format) or to a substance capable of specifically binding to the ligand (in a sandwich format). Providing a second reagent having a detectable physical property comprising a sol particle bound to a substance capable of specifically binding the ligand and / or a ligand analog (if present); Mixing the second reagent and the fluid sample and detecting, before, during or after the reaction, a change in the physical property of the sol particles that is a qualitative or quantitative indicator of the ligand in the fluid sample. . These reagents bind to each other as a function of the presence of the ligand in the sample, resulting in a change in the physical properties of the sol particles related to the degree of binding of the reagents. The present invention also provides a kit for detecting the presence of a ligand in a liquid sample or measuring the amount thereof. The invention further provides an immunological conjugate having a detectable physical property. |
priorityDate | 1996-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 206.