http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H11504946-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-235 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-235 |
| filingDate | 1996-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1999-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H11504946-A |
| titleOfInvention | Anti-glucocorticoid drug |
| abstract | (57) [Summary]nThe present invention relates to the pharmaceutical and veterinary fields, particularly to non-steroidal anti-glucocorticoids. It is an object of the present invention to establish a new class of drugs with low toxicity and high activity in regulating the sensitivity of mammalian cells to glucocorticoid hormones. Inhibits insect pheromones with long-chain aliphatic non-steroidal chemical structures, or their synthetic homologues or derivatives that are unsaturated aliphatic alcohols, aldehydes or esters, specifically from exerting the effects of glucocorticoid hormones on mammalian cells There are new applications to use for. The aliphatic carbon chain length of these pheromones varies from 10 to 21 carbon atoms. It is also possible that two or more pheromones and / or their synthetic homologues or derivatives may be applied in combination to enhance therapeutic activity. In this case, the selection is made on the basis of the different hydrophobicity in proportion to the aliphatic carbon chain length. These differences in chain length must have 5 or more carbon atoms. Formulation examples of pharmaceutical dosage forms and the results of comparative experiments showing their high activity are disclosed. |
| priorityDate | 1996-01-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.