http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H11504932-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-90 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-90 |
| filingDate | 1996-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1999-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H11504932-A |
| titleOfInvention | Preparation method of lercanidipine hydrochloride |
| abstract | (57) [Abstract] The acid halide of 2,6-dimethyl-5-methoxycarbonyl-4- (3-nitrophenyl) -1,4-dihydropyridine-3-carboxylic acid is converted to 2, N in an aprotic solvent. Methyl 1,1, N-trimethyl-N- (3,3-diphenyl) of general formula I, including reacting with -dimethyl-N- (3,3-diphenylpropyl) -1-amino-2-propanol. A method for preparing propyl) -2-aminoethyl 1,4-dihydro-2,6-dimethyl-4- (3-nitrophenyl) -pyridine-3,5-dicarboxylate (lercanidipine). The product can be separated by industrially applicable crystallization techniques and is obtained in high yield as its anhydrous hydrochloride, a form with high stability and low hygroscopicity. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006504800-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005504045-A |
| priorityDate | 1995-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 97.