| abstract |
(57) Abstract: The present invention provides a compound of the general formula (R) -enantiomer in the form of a first component (a) which is a 5-HT reuptake inhibitor and a free base or a pharmaceutically acceptable salt thereof. (I) Wherein R 1 is n-propyl or cyclobutyl; R 2 is isopropyl, tertiary butyl, cyclobutyl, cyclopentyl or cyclohexyl; R 3 is hydrogen; R 4 is hydrogen or methyl A) a selective 5-HT 1A antagonist, a combination of the second component (b), a method of making the combination, a pharmaceutical formulation containing the combination, and the use of the combination such as depression, anxiety and OCD Uses and methods for treating emotional disorders and kits containing the combinations. |