| abstract |
The present invention provides novel hydroxamic acids, carbocyclic acids and derivatives thereof, pharmaceutical compositions, and these novel compounds to inhibit matrix metalloproteinases such as stromelysin and other matrix metalloproteinases. Provide a way to use. The compounds of the present invention also inhibit the production of tumor necrosis factor (TNF), and are therefore useful in treating arthritis and other related inflammatory diseases. These new compounds have the formula (I) Is represented by |