| abstract |
(57) [Summary]nA Pakistan-derived hepatitis E virus strain (SAR-55), which is involved in non-A and non-B hepatitis, which is an enteric infectious disease, is known. The present invention, described as the entire structural region of SAR-55, ie, open reading frame 2 (ORF-2), relates to expression in a eukaryotic cell expression system. The expressed protein can form HEV virus-like particles, which are used as antigens in diagnostic immunoassays and as immunogens or vaccines to resist hepatitis E infection. Can be. |