http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H1149774-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e43b4ca6b41ce9f54c9a895d474c81a |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04 |
| filingDate | 1997-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e360f58e669d67426b4cb781575649e1 |
| publicationDate | 1999-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H1149774-A |
| titleOfInvention | Method for demethylation of podophyllotoxin |
| abstract | (57) [Summary] (with correction) [PROBLEMS] To efficiently demethylate podophyllotoxin without using a harmful halogen solvent to obtain 4′-demethyl-4-epipodophyllotoxin. SOLUTION: One part by weight of podophyllotoxin is 1 to 1 part by weight. Demethylation with hydrogen bromide in 9 to 9 parts by volume of a non-halogenated organic solvent to obtain a reaction intermediate represented by the following formula (2), which is hydrolyzed by the following formula (3) A method for producing the indicated 4'-demethyl-4-epipodophyllotoxin. |
| priorityDate | 1997-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 48.