| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f7c7159366be37ecf8a4c595cfa235a8 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 |
| filingDate |
1997-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a096fc429843e347f57276123042bee4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f253280451905ecda1057d4100ee21f6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c62867a629d65d6df7b4bf6cb9a954a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dffcf5a58c8a8b432b9d336df2b82a69 |
| publicationDate |
1999-02-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-H1135493-A |
| titleOfInvention |
Novel anti-estrogen gene therapy |
| abstract |
(57) Abstract: A novel anti-estrogen gene therapeutic comprising a DNA encoding nuclear receptor TR4 or a mutant thereof as an active ingredient. [Effects] The anti-estrogen gene therapeutic agent of the present invention is a therapeutic or preventive agent for diseases that develop or progress in an estrogen-dependent manner. Particularly, since the anti-estrogen gene therapeutic agent of the present invention exerts an effect on cells derived from bone, it is effective for osteosarcoma, which is a bone disease progressed by the action of estrogen, or bone metastatic cancer derived from breast cancer. It is a therapeutic or prophylactic agent. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03033529-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03033529-A3 |
| priorityDate |
1997-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |