http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H11349598-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2de3beee83d9c19278da409b72c777a8 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
| filingDate | 1998-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_366220bc27974f00460e1a5e4659dd80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30a325b802f9964831568d88e1eb2fc5 |
| publicationDate | 1999-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H11349598-A |
| titleOfInvention | Vascular endothelial cell growth inhibitor and its use |
| abstract | (57) [Summary] [Constitution] An endoregulin, a purification method thereof, an antibody thereof, a pharmaceutical composition containing them, and a method of screening for an agonist or antagonist thereof. [Effect] The endoregulin of the present invention is a factor produced by macrophages and specifically suppresses the proliferation of vascular endothelial cells without affecting vascular smooth muscle. Agonists of endoregulin, including endoregulin, suppress the growth of endothelial cells in blood vessels, so the growth of solid cancer, cancer metastasis, diabetic retinopathy, atherosclerosis, neovascular glaucoma, rheumatism It can be used for prevention / treatment of osteoarthritis. In addition, antibodies for endoregulin Promoting angiogenesis can normalize abnormalities that occur in ovulation, placenta formation and wound healing. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2003534857-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-4898068-B2 |
| priorityDate | 1998-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 190.