| abstract |
PROBLEM TO BE SOLVED: To obtain FO-6903A and B biologically active substances having a novel structure having an interleukin 1 beta converting enzyme inhibitory action and a sphingomyelinase inhibitory action, and a method for producing the same. SOLUTION: FO-6903 belonging to the genus Trichoderma A microorganism having the ability to produce the A and B substances is cultured in a medium, the FO-6903A and B substances are accumulated in the culture, and the FO-6903A substance and / or the FO-6903B substance are collected from the culture. . |