| abstract |
(57) [Summary] (Modifications) [Problem] To provide an SBHUNC50 polypeptide and a SBHUNC50 polynucleotide. SOLUTION: SBHU comprising an amino acid sequence having at least 97% identity to a specific amino acid sequence A SBHUNC50 polynucleotide comprising a NC50 polypeptide and a nucleotide sequence having at least 90% identity to the nucleotide sequence of SEQ ID NO: 1 is obtained. [Effect] SBHUNC50 polypeptide and polynucleotide are used for epilepsy, convulsions, migraine, neuromuscular disorders, neurodegeneration, It is useful in treating dysfunctions or diseases, including developmental disorders and psychiatric disorders, and in diagnostic assays for such diseases. |