abstract |
(57) [Problem] To provide a terpenoid lactone compound, a method for producing the same, and a pharmaceutical composition containing the compound. SOLUTION: The compound is represented by the formula (I): [For example, [5bS- (1aR * , 5bβ, 8aα, 8bα, 10aα, 10bβ)]-5b, 6, 7,8,8a, 8b, 10a, 10b-octahydro- 2-hydroxy-5b, 8a-dimethyl-2H, 4H, 9H-Flo [2 ', 3', 4 ': 4,5] oxireno [2,3] naphtho [2,1-c] pyran-4,9-dione]. The production method is as follows: Oidiodendron griseum (FE) RM BP-5778), or a mutant or recombinant thereof. |