| abstract |
[PROBLEMS] To provide a benzoxazine derivative having excellent inhibitory activity against a protease [particularly, a protease derived from human cytomegalovirus (HCMV)] or a pharmacologically acceptable salt thereof. Provided is a therapeutic or preventive agent for a viral infection, particularly a human cytomegalovirus (HCMV) infection, as an active ingredient. SOLUTION: General formula [Wherein, R 1 a, R 1 b, R 1 c, R 1 d: H, C 1 -C 6 alkyl group, C 3 -C 6 cycloalkyl group, C 6 -C 10 aryl group, 5 to 6 membered heteroaryl - group, a halogen atom, hydroxy group, C 1 -C 6 alkoxy group, C 1 -C 6 alkylthio group, amino group, such as C 1 -C 6 alkylamino group; R 2 : C 6 -C 10 aryl group, 5- to 6-membered heteroaryl group] or a pharmaceutically acceptable salt thereof. |