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filingDate 1998-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9d1633777996e85b4848ff6326d0efa
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publicationDate 1999-11-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-H11318450-A
titleOfInvention Method for evaluating substances that control the transformation of smooth muscle cells
abstract (57) Abstract: A method for evaluating a substance that controls the transformation of smooth muscle cells utilizing the property that BTEB2 protein binds to a protein promoter that exacerbates arteriosclerosis and induces high expression activity, And to provide a host cell used in such an evaluation method. SOLUTION: A host cell having at least a first vector containing a promoter having a DNA site binding to BTEB2 and a gene encoding a reporter product operably linked downstream thereof is evaluated with BTEB2 by using a host cell. A method for evaluating a substance that controls transformation of a smooth muscle cell, comprising expressing the reporter product in a host cell in the presence of a substance, and then detecting the reporter product.
priorityDate 1998-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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