| abstract |
(57) Abstract: Use of a neutral or cationic polymer for preventing activation of blood and plasma upon contact with a semipermeable membrane. The use of a neutral or cationic polymer to prevent the activation of blood or plasma contact surfaces in contact with a semi-permeable membrane based on polyacrylonitrile with a constant negative charge. The membrane is attached to a device for processing blood or plasma by extracorporeal circulation, but before or after the formation of the membrane, Moreover, prior to its sterilization, the electrical properties of the membrane, ie, the zeta potential "Z" and the electrical resistivity "R", are modified by combining it with a neutral or cationic polymer to give -Log 10 (| Z | / R), the electrokinetic index “I” corresponding to 0.8 or less, or the positive zeta potential “Z” in the range of 0 to 15 mV (excluding upper and lower limits). Or to meet. |