| abstract |
PROBLEM TO BE SOLVED: To provide a novel benzocyclobutane compound which acts as a potent inhibitor of serotonin reuptake and as an inhibitor of noradrenaline reuptake, a method for producing them, and a pharmaceutical composition containing them. SOLUTION: Formula (I): Wherein, Z 1, Z 2, Z 3 ε beauty Z 4 may be the same or different, represents a group each as defined in the detailed description of the invention, X represents an oxygen atom, a group S (O) p, - (CH 2) n or - CH 2 βYβCH 2 β wherein p, n and Y are as defined in the detailed description of the invention, and A is a formula: Wherein m, R 1 , R 2 and G are as defined in the detailed description of the invention, or an isomer thereof or an addition salt thereof with a pharmaceutically acceptable acid. . |