abstract |
PROBLEM TO BE SOLVED: To provide a method for preparing polypeptide fine particles having high recovery and high purity without denaturation. SOLUTION: A mixed aqueous solution of a polypeptide and polyethylene glycol is freeze-dried, and an organic solvent which does not dissolve the polypeptide but dissolves the polyethylene glycol is added to the obtained solid, and the polyethylene glycol in the solid is added. Is dissolved to obtain polypeptide fine particles. |