| abstract |
(57) [Summary] (With correction) [PROBLEMS] To chemically modify or label a polynucleotide or the like so as to facilitate detection. SOLUTION: The following general formula (Wherein P is a phosphate residue, S is a sugar or monosaccharide residue, B is a base residue, and when the nucleotide is a deoxyribonucleotide, a phosphate residue The group is 3 'and / or 5' of the sugar residue At the 2 ', 3' and / or 5 'positions if the nucleotide is a ribonucleotide, the base is a purine or pyrimidine, and the base is a pyrimidine or purine, respectively. Has the above-mentioned base bound from the N1 or N9 position to the 1 ′ position of the sugar residue, Said Sig is a chemical residue covalently linked to the sugar or monosaccharide residue S of the nucleotide and can itself be a signal, or can itself detect itself or signal its presence. Things. ) |