http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H1128092-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f7c7159366be37ecf8a4c595cfa235a8 |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 |
filingDate | 1997-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c83d3101990a3908a54868460f480956 |
publicationDate | 1999-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-H1128092-A |
titleOfInvention | Novel protein OPF or 5 and its gene |
abstract | (57) [Summary] (Solution) [PROBLEMS] OPF or 5 having differentiation-inducing activity from bone marrow cells to cells having hydroxyapatite decomposability, proteins similar to OPF or 5, peptide fragments of these proteins, antibodies , Medicines containing these proteins as active ingredients, genes encoding these proteins, expression vectors of the genes, transformants into which the expression vectors have been introduced, methods for producing recombinant proteins using the transformants, the genes Use of the protein in screening for an inhibitor of the activity of inducing differentiation of a transgenic animal or a bone marrow cell into a cell having the ability to degrade hydroxyapatite, which has been introduced or deleted. [Effect] The novel protein OPF-5 has an activity of inducing the differentiation of bone marrow cells into cells having the ability to degrade hydroxyapatite, and thus can be applied to a wide range of diseases to be treated by exerting this function. |
priorityDate | 1997-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 590.