| abstract |
(57) [Summary] (Modifications) [PROBLEMS] To provide a compound having melatonin receptor affinity and receptor subtype selectivity, which is useful for treatment of a pathological condition related to melatonin action. SOLUTION: Formula (I): Wherein the A and B rings together form a naphthalene or the like; T is an alkyl or the like; R is a hydrogen atom, an OR ′ group or the like (R ′ is an alkyl or the like) (R ′ is an alkyl or the like), or R is together with the adjacent carbon atom form a 5- to 7-membered ring; G 1 is such cycloalkyl; and G 2 is the formula (G 2 0) ~ (G 2 2): (Wherein, X is oxygen, etc.; R 2 is hydrogen, and the like; and R 2 1 is an alkyl group or the like), a compound represented by], their enantiomers, diastereoisomers, or pharmaceutically acceptable acid or Its addition salt with a base. |