abstract |
(57) [Problem] To provide an antitumor substance having a selective growth inhibitory activity on tumor cells. SOLUTION: It is an antitumor substance derived from a medicinal plant (for example, mugwort, dandelion, horsetail, horsetail, oshimazakura, yoshino cherry, bracken). The high molecular weight active substance has a molecular weight of 3,500 or more as measured by a dialysis membrane, is salted out by 90% ammonium sulfate, and its activity is reduced by heat treatment. The low-molecular-weight active substance has a molecular weight of 3,500 or less as measured by a dialysis membrane, is extracted with an organic solvent, is a neutral or acidic substance, and can be separated by developing with an appropriate solvent system using HPTLC. |