http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H11239478-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2f8cfa5aee4410611b5c562275c9f8e3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-62 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-04 |
| filingDate | 1998-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e4a3d36b911cc64a503760f3eeff9ce |
| publicationDate | 1999-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-H11239478-A |
| titleOfInvention | Method for producing optically active alcohol containing halogen substitution |
| abstract | (57) Abstract: Optically active 4-halo-3 having high optical purity -Efficiently synthesize hydroxybutyrate. SOLUTION: The asymmetric reduction of a halogen-substituted ketone such as a 4-haloacetoacetate is carried out at a low temperature by using a secondary alcohol dehydrogenase and an alcohol as a substrate for NADH regeneration, thereby obtaining an optically active 4-halo-3. -Synthesis of an optically active alcohol containing a halogen substitution such as hydroxybutyric acid ester. [Effects] Reduction of toxicity of enzymes to ketones having halogen substitution such as 4-haloacetoacetate and optically active alcohols having halogen substitution such as 4-halo-3-hydroxybutyrate by reacting at a low temperature. As a result, the optically active 4-halo-3 is maintained while maintaining the high stereoselectivity of the secondary alcohol dehydrogenase. -Accumulation concentration of optically active alcohol containing halogen substitution such as hydroxybutyric acid ester can be increased. |
| priorityDate | 1998-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 310.