| abstract |
PROBLEM TO BE SOLVED: To provide a preventive and therapeutic agent for a disease caused by excessive apoptosis, for example, AIDS. SOLUTION: General formula [I] (Wherein, R 1 represents an optionally substituted aryl group or an optionally substituted heteroaryl group, and R 3 represents a lower alkyl group, a lower alkoxy group, a cycloalkyl group, a lower alkynyl group, or an optionally substituted Represents an aryl group or a heteroaryl group which may be substituted, R 4 represents a hydrogen atom, a hydroxyl group, a halogen atom or a lower alkyl group, R 5 represents a hydrogen atom or a halogen atom, or R 4 and R 5 Together represent an oxo group, R 21 represents a hydrogen atom or a lower alkyl group, ring A represents a benzene ring, a pyridine ring or a thiophene ring, and W represents a nitrogen atom or a CH group. Or a pharmaceutically acceptable salt thereof. |