abstract |
PROBLEM TO BE SOLVED: To provide a novel pyrrole compound as an inhibitor of cyclooxygenase-2, interleukin-1β and induced nitric oxide synthase. SOLUTION: A pyrrole compound which is, for example, 1,3-di- (4-fluorophenyl) -4,7-methano-4,5,6,7-tetrahydro-2H-isoindole. |